• 国家级·西安经济技术开发区————西部网 陕西头条 2019-08-24
  • 招聘凤凰网招聘电商文案策划人员 虚左以待 2019-08-14
  • 对啊网智能招聘产品上线 学习记录也能助力好工作 2019-08-14
  • 马尔克斯:多年以后,奥雷连诺上校站在行刑队面前 2019-08-07
  • 西部网(陕西新闻网)www.cnwest.com 2019-08-07
  • 买房才能幸福?我就要做名下没有任何房产的清贫青年 2019-08-03
  • 第二届“为了明天关爱青少年彩虹行动”微电影大奖赛 2019-08-01
  • 火场上的那双手,找到了! 2019-08-01
  • 敢想敢拼的邹市明:用奥运精神助推青少年体育事业发展 2019-07-30
  • 让十九大精神在基层生根 2019-07-30
  • 讲政德如何落到实处(专家观点) 2019-07-24
  • 一语惊坛(6月7日):祝考生旗开得胜! 2019-07-23
  • 全区生态环境保护大会召开 2019-07-23
  • 春节我在岗:爸妈,儿子在军营给您们拜年了 2019-07-20
  • 先学别人后自己创造创新,先进口后出口等都是发展的必然。只有这“先”而没有那“后”就发展不了。 2019-07-17
  • 客服热线:400-901-9800          客服QQ:4009019800          技术答疑   技术支持   质量反馈   人才招聘   联系我们
    首页 > 产品中心 > 一抗 > 产品信息
    Rabbit Anti-NeuN antibody (bs-1613R)
    订购热线:400-901-9800
    订购邮箱:[email protected]
    订购传真:010-58129612
    技术支持:[email protected]
    说明书: 50ul  100ul  200ul
    20ul/480.00元
    50ul/880.00元
    100ul/1580.00元
    200ul/2480.00元
    大包装/询价

    产品编号 bs-1613R
    英文名称 NeuN
    中文名称 神经元核抗原抗体
    别    名 FOX3; NeuN; neuronal nuclei antigen; neuronal nuclei; Vertebrate neuron-specific nuclear protein; Neuna60; Neuronal nuclear antigen A60; RNA binding protein fox-1 homolog 3 isoform 1; RNA binding protein, fox 1 homolog (C. elegans) 3; Rbfox3; D11Bwg0517e; Fox-3; Fox3; Hrnbp3; RP23-159O6.5; novel protein; Fox-1 homolog C; fox1 homolog C; FLJ56884; FLJ58356; hexaribonucleotide binding protein 3 RFOX3_HUMAN.  
    Specific References  (10)     |     bs-1613R has been referenced in 10 publications.
    [IF=7.69] Zhao, Wenjuan, et al. "Human APOE Genotype Affects Intraneuronal Aβ1-42 Accumulation in a Lentiviral Gene Transfer Model." Human Molecular Genetics (2013): ddt525.  Mouse.  
    [IF=3.73] Yu, Lu, et al. "Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroinflammation by Inhibiting the Activation of NF-κB and STAT3 in Transient Focal Stroke." PloS one 8.2 (2013): e55839.  Rat.  
    [IF=3.12] Jiang, W., et al. "Curculigoside A attenuates experimental cerebral ischemia injury< i> in vitro and< i> vivo." Neuroscience 192 (2011): 572-579.  Rat.  
    [IF=2.88] Li, Hongwei, et al. "Regular treadmill running improves spatial learning and memory performance in young mice through increased hippocampal neurogenesis and decreased stress." Brain Research (2013).  Mouse.  
    [IF=2.59] Jiang, Wang-Lin, et al. "Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury." European journal of pharmacology 640.1 (2010): 75-81.  IHC-P ;  Rat.  
    [IF=5.20] Zhao, Wenjuan, et al. "Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector." Frontiers in Aging Neuroscience 6 (2014): 210.  IHC-P ;  Mouse.  
    [IF=3.92] Wei, Gang, et al. "β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice." Journal of Alzheimer's Disease 33.3 (2013): 863-880.  IF(ICC) ;  Mouse.  
    [IF=1.56] Hu, Hai Xia, et al. "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. Corrigendum in/mmr/12/3/3998." Molecular medicine reports 12.1 (2015): 1321-1327.  IHC-P ;  Rat.  
    [IF=2.05] Kopec, Ashley M., et al. "Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue." Journal of Neuroscience Methods (2017).  WB ;  Rat.  
    [IF=2.00] Wang, Jun, et al. "Anti‐inflammatory and retinal protective effects of capsaicin on ischemia‐induced injuries through the release of endogenous somatostatin." Clinical and Experimental Pharmacology and Physiology (2017).  IHC-P ;  Mouse.  
    研究领域 细胞生物  神经生物学  转运蛋白  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, 
    产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 34kDa
    细胞定位 细胞核 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NeuN:51-150/312 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

    Function:
    RNA-binding protein that regulates alternative splicing events.

    Subcellular Location:
    Nucleus. Cytoplasm.

    Similarity:
    Contains 1 RRM (RNA recognition motif) domain.

    SWISS:
    A6NFN3

    Gene ID:
    146713

    Database links:

    南粤风采36选7最新开奖 www.gtxm.net Entrez Gene: 146713 Human

    Entrez Gene: 52897 Mouse

    Entrez Gene: 287847 Rat

    SwissProt: A6NFN3 Human

    SwissProt: Q8BIF2 Mouse

    Unigene: 135229 Human

    Unigene: 341103 Mouse

    Unigene: 143966 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    神经生物学相关蛋白(Neurobiology)
    产品图片
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (bs-0295G-FITC) for 90 minutes, and DAPI for nuclei staining.
    Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuN) Polyclonal Antibody, Unconjugated (bs-1613R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (bs-0295G-FITC) for 90 minutes, and DAPI for nuclei staining.
    Positive control: RSC96
    Isotype Control Antibody: Rabbit IgG;
    Secondary Antibody: Goat anti-rabbit IgG-FITC, Dilution: 1:200 in 1 X PBS containing 0.5% BSA
    Primary Antibody catalog number: bs-1613R, Dilution: 3μg in 100 μl 1X PBS containing 0.5% BSA
    版权所有 2016-2020 南粤风采36选7最新开奖 www.gtxm.net 北京博奥森生物技术有限公司 京ICP备05066980号 京公网安备110107000727号
    通过国际质量管理体系ISO9001:2008 GB/T19001-2008认证    编号:00115Q211807R1M/1100
  • 国家级·西安经济技术开发区————西部网 陕西头条 2019-08-24
  • 招聘凤凰网招聘电商文案策划人员 虚左以待 2019-08-14
  • 对啊网智能招聘产品上线 学习记录也能助力好工作 2019-08-14
  • 马尔克斯:多年以后,奥雷连诺上校站在行刑队面前 2019-08-07
  • 西部网(陕西新闻网)www.cnwest.com 2019-08-07
  • 买房才能幸福?我就要做名下没有任何房产的清贫青年 2019-08-03
  • 第二届“为了明天关爱青少年彩虹行动”微电影大奖赛 2019-08-01
  • 火场上的那双手,找到了! 2019-08-01
  • 敢想敢拼的邹市明:用奥运精神助推青少年体育事业发展 2019-07-30
  • 让十九大精神在基层生根 2019-07-30
  • 讲政德如何落到实处(专家观点) 2019-07-24
  • 一语惊坛(6月7日):祝考生旗开得胜! 2019-07-23
  • 全区生态环境保护大会召开 2019-07-23
  • 春节我在岗:爸妈,儿子在军营给您们拜年了 2019-07-20
  • 先学别人后自己创造创新,先进口后出口等都是发展的必然。只有这“先”而没有那“后”就发展不了。 2019-07-17
  • 平特一肖图片今晚的 陕西快乐10分开奖直播现场 昆明手机号码选号 快三开奖查询 新疆十一选五技巧视频 超级大乐透开奖公告 中国彩吧一更懂彩民l 立博足球指数捷报网 青海11选5啊彩网 2012289期p3试机号 2013全年平码特码 山西快乐十分开奖结果查询结果 黄大仙图片两码中特 喜乐彩开奖号码信息 六合彩管家婆